Histamine intolerance during perimenopause may worsen due to fluctuating estrogen levels, declining progesterone, mast cell activation, gut dysfunction, inflammation, and nervous system stress. Symptoms such as anxiety, insomnia, flushing, migraines, food sensitivities, and palpitations may intensify during hormonal transition years as estrogen and histamine influence each other bidirectionally.
Read MoreWeight loss resistance is often driven by deeper physiologic regulation—not effort. This article explains why weight loss can stall despite healthy habits using a functional medicine, root-cause framework.
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